AHIVpositivepatient

ProgressivecognitiveimpairmentinanHIV-positivepatient2weekafterhighlyactiveantiretroviraltherapy(HAART,高效抗逆转录病毒治疗)。

Whatisyourdiagnosis?

TheanswerisProgressiveMultifocalLeukoencephalopaty-ImmuneReconstitutionInflammatorySyndrome(IRIS)(免疫重建炎症综合征引起的进行性多灶性白质脑病)

Immunereconstitutioninflammatorysyndrome(IRIS)(alsoknownasimmunerecoverysyndrome)isaconditionseeninsomecasesofAIDSorimmunosuppression,inwhichtheimmunesystembeginstorecover,butthenrespondstoapreviouslyacquiredopportunisticinfectionwithanoverwhelminginflammatoryresponsethatparadoxicallymakesthesymptomsofinfectionworse.

CNSimmunereconstitutioninflammatorysyndrome(IRIS)isaT-cell-mediatedencephalitisthatoccursin15–35%ofAIDSpatientsunderHAARTtherapy.

Progressivemultifocalleukoencephalopaty(PML)isanopportunisticinfectionthatdevelopsinimmunosuppressedHIVpatients.

SomeofthesepatientsmaydevelopPMLduring







































治疗白癜风得花多少钱
北京治疗白癜风的医院